Debating whether the GOP will reverse the Keystone decision, and partisan politics on Capitol Hill, with Rep. Charlie Rangell, (D-NY), and Rep. David Schweikert, (R-AZ).
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TUESDAY, Jan. 17 (HealthDay News) -- There's more evidence that use of the oral contraceptive pill can help ease the cramps, bloating and other pain some women experience during their period.
Some previous research, as well as anecdotal evidence, have suggested that the Pill could help women with painful periods, but a 2009 review of all available research concluded there was limited evidence for such a conclusion.
The new findings, from a Swedish study that has been running for 30 years, show that women who used the combined birth control pill (estrogen plus progestin) suffered less severe pain than women who did not use the Pill, the researchers said.
Their study findings appear online Jan. 18 in the journal Human Reproduction.
Experts estimate that pain associated with menstrual periods accounts for 600 million lost working hours and $2 billion in lost productivity in the United States each year.
One expert in the United States noted that doctors have long used the Pill to help ease such symptoms.
"Many obstetrician/gynecologists have used oral contraceptive pills to help alleviate menstrual pain, otherwise known as dysmenorrhea," said Dr. Jenifer Wu, an obstetrician/gynecologist at Lenox Hill Hospital in New York City. "This is technically an off-label use of these commonly prescribed medications," she added.
The Swedish researchers noted that younger women typically suffer more from painful periods than older women. And while they did find that symptoms eased somewhat with increasing age, the effects of age and Pill use were independent of each other and use of the Pill had a greater effect overall.
The study included three groups of women who turned 19 in 1981, 1991 and 2001. Each group included 400 to 520 women, who were asked about their pattern of menstruation and menstrual pain, reproductive history, contraceptive use, height and weight.
The women provided this information at ages 19 and 24.
"By comparing women at different ages, it was possible to demonstrate the influence of [the Pill] on the occurrence and severity of dysmenorrhea, at the same time taking into account possible changes due to increasing age," Dr. Ingela Lindh, of the Institute of Clinical Sciences, Sahlgrenska Academy at Gothenburg University, said in a journal news release. "We found there was a significant difference in the severity of dysmenorrhea depending on whether or not the women used combined oral contraceptives."
Dr. Steven Goldstein, an obstetrician/gynecologist at NYU Langone Medical Center in New York City, said: "The study results are not surprising. It's gratifying to see researchers documenting scientifically what practitioners have been seeing for a very long time. The amount of discomfort from a woman's period with a combination birth control pill is a fraction of what it is without the Pill. There is a diminution of pain from the Pill."
For her part, Wu believes that "doctors should include a discussion of all the benefits and risks when presenting birth control options, and the improvement of dysmenorrhea is a significant benefit to oral contraceptive pills."
More information
The U.S. National Library of Medicine has more about dysmenorrhea.
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Chemotherapy pushes AML cancer cells toward a corner -- the protein WEE1 helps them brake to stay on track. Take away WEE1 and AML cells hit the wall. (Photo courtesy of Flickr user ShinyThings, cc license.)
A study published this week in the journal Leukemia identifies a mechanism that acute myeloid leukemia (AML) cells use to evade chemotherapy ? and details how to close this escape route.
?Introducing chemotherapy to cells is like putting a curve in front of a speeding car,? says Christopher Porter, MD, investigator at the University of Colorado Cancer Center and assistant professor of pediatrics at the University of Colorado School of Medicine. ?Cells that can put on the brakes make it around the corner and cells that can?t speed off the track.?
Porter and colleagues collaborated with James DeGregori, PhD, CU Cancer Center investigator and professor of biochemistry and molecular genetics at the CU School of Medicine to define a molecular braking process that AML cells use to survive the curves of chemotherapy. They also showed that when this molecular brake is removed, AML cells (but not their healthy neighbors) die on the corners.
The discovery of this escape route and how to plug it provides hope for survival for a greater proportion of the estimated 12,950 people diagnosed with AML every year in the United States.
The group?s findings rely on the relatively new technique of functional genomic screening of AML cells, accomplished by the CU Cancer Center Functional Genomics Shared Resource at the University of Colorado Boulder.
Using techniques they developed, the group turned off a different gene in each of a population of AML cells all at once. Then? they hit all cells with chemotherapy traditionally used for AML. The goal: to see which genes, when turned off, would make the cells especially susceptible to chemo.
Chris Porter, MD, investigator at the University of Colorado Cancer Center and assistant professor of pediatrics at the University of Colorado School of Medicine
In this study, which generated over 30 million data points, cells that lacked a gene to make something called WEE1 died in disproportionate numbers. When you turn off WEE1, cancer cells die.
?WEE1 is the brakes,? Porter says. ?With chemotherapy we introduce DNA damage in cancer cells ? we push them toward the curve hopefully at a greater rate than healthy cells. If WEE1 is there, cancer cells can round the curve. Without it, they flip.?
Hidden in Porter?s words is an element that makes this an especially exciting finding: AML cells may be more dependent than are healthy cells on WEE1. And so when you inhibit WEE1, you strip the brakes from cancer cells but not their healthy neighbors, killing AML cells but leaving healthy cells able to corner on rails.
?I?m optimistic that this will eventually lead to a therapeutic regimen that allows us to target AML cells that have escaped conventional therapies,? Porter says.
Porter calls the team?s initial results combining a drug that inhibits WEE1 with chemotherapy in mouse models of AML, ?extremely promising.?
?In light of these data, we are already early in the clinical trial planning process,? Porter says.
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This work was supported by the Colorado Golfers Against Cancer and the AMC Cancer Fund, the Leukemia and Lymphoma Society, and the National Cancer Institute through the University of Colorado Cancer Center (3P30CA046934-22S).
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LOS ANGELES?? Two women walking dogs in the Hollywood Hills found a human head in a plastic bag, Los Angeles police said.
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The women made the discovery on a popular trail below the Hollywood sign Tuesday afternoon, police said.
"Two of the dogs began to play with the bag and what appeared to be an object. While the dogs were playing with it, at some point the object came out of the bag and they discovered that it was a head ? a severed head," Sgt. Mitzi Fierro told KCAL-TV.
The bag was visible from the trail, she said.
The Los Angeles Times cited sources as saying it appeared to be from a man in his 40s with "salt-and-pepper" hair.
TMZ reported that one of the dog walkers who found the head asked a passer-by if she could use his phone to call the police. After he obliged, the man took a photo of the head. The picture is now up for sale. According to TMZ, it depicts a male's bloody head, with very red and slightly decomposed skin.
Not there long
Police believe the severed head had not been at the site for a long time, based in part on the fact that there were no animal bites on it.
"There's not a lot of signs of decomposition yet," Fierro said.
The women who discovered the bag work as dog walkers and had about nine dogs with them at the time, Officer Karen Rayner said.
Investigators hope to come up with a sketch of the victim in order to identify who he is, Fierro said. Coroner's investigators also will attempt to identify the victim through dental records.
Police used cadaver dogs to assist in the search for further human remains until dusk, when they called off the investigation until daylight returns.
The crime scene was being guarded by police. NBC Los Angeles reported that detectives returned to the site Wednesday morning. The investigation is being handled by LAPD?s Robbery-Homicide Division.
The stretch of road where the head was found is a hiking trail popular with local residents, especially dog walkers.
The trail also passes by the "Batcave," which was used in the original Batman and Robin series.
The Associated Press and Reuters contributed to this report.
Source: http://www.msnbc.msn.com/id/46036506/ns/us_news-crime_and_courts/
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Eugenie Scott, executive director of the National Center for Science Education, long the nation's leading defender of evolution education, discusses the NCSE's new initiative to help climate science education.
January 16, 2012
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Eugenie Scott, executive director of the National Center for Science Education, long the nation's leading defender of evolution education, discusses the NCSE's new initiative for climate science education. ??
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A choir comprised of African children orphaned by AIDS, war and poverty is scheduled to perform original music, dance routines and storytelling in Surrey and Delta this month.
Each of the members of the Watoto Children's Choir has suffered the loss of one or both parents. They live in children's villages in Uganda, where they receive care and education courtesy of Watoto ? a program founded by Canadians Gary and Marilyn Skinner in 1994 to address the Uganda orphan crisis. According to Watoto, in sub-Saharan Africa HIV/AIDS has orphaned more than 14 million children. The program currently provides care and long-term education for over 2,500 orphaned and abandoned children.
Watoto Children's Choirs have toured Canada, the United States, Europe, the United Kingdom, Australia, New Zealand, Hong Kong, Asia, Uganda, South Africa, Israel and Brazil.
The 2012 tour is entitled Beautiful Africa: A New Generation. Performances are free of charge, but merchandise, including CDs, DVDs, T-shirts, African jewelry and craft items made by women in the Watoto program, will available for purchase.
Funding for Watoto is made possible through free will offerings at the end of each performance as well as donations from individuals, businesses, churches, groups and communities.
Locally, performances take place Jan. 18, 7 p.m. at North Delta Evangelical Church, 11300 84 Ave.; Jan. 22, 7 p.m. at Relate Church, 6788 152 St.; Jan. 25, 7 p.m. at Delta Church, 7696 112 St.; Jan. 29, 9 a.m. and 11 a.m. at Cedar Grove Baptist Church, 10330 144 St.; and Jan. 29, 6:30 p.m. at Surrey Pentecostal Church, 16870 80 Ave.
Visit www.watoto.com for more information.
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Source: http://www.surreyleader.com/entertainment/137444108.html
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LAGOS, Nigeria (AP) ? An offshore rig exploring possible oil and gas fields off Nigeria's coast for Chevron Corp. caught fire Monday, and the oil company said officials were still trying to account for all those working there.
Chevron said two workers were missing and 152 others found, but gave no further detail on the missing persons.
The company said it was still investigating the fire, which occurred near its North Apoi oil platform, and which forced it to shut down.
"We immediately flew out people to the nearby North Apoi platform, and have been helping those needing any medical assistance," Chevron spokesman Scott Walker said in a statement.
Chevron did not immediately say what caused the fire. However, Nigeria's government believes a "gas kick" ? a major build up of gas pressure from drilling ? was responsible, said Levi Ajuonoma, a spokesman for the state-run Nigerian National Petroleum Corp.
Chevron and other foreign oil companies in Nigeria pump crude oil in partnership with the state-run company.
Nnimmo Bassey, who runs an environmental watchdog group in Nigeria, said he had received reports from locals nearby that the fire was an industrial incident.
"Workers were trying to contain the gas pressure and they didn't succeed," Bassey said.
The rig is run on Chevron's behalf by contractor FODE Drilling Co., Walker said. Officials with FODE, which has offices in London and Jenkintown, Pennsylvania, could not be immediately reached for comment Monday.
Nigeria is the fifth-largest crude oil exporter to the U.S. It produces about 2.4 million barrels of crude oil a day. However, more than 50 years of oil production has seen environmental damage through delta's maze of muddy creeks and mangroves.
Chevron, based in San Ramon, California, produced an average of 524,000 barrels of crude oil a day from Nigeria in 2010. The company has exploration rights to about 2.2 million acres across Nigeria's delta and offshore.
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